SARMs 101: DOSAGE, RESULTS, SIDE-EFFECTS & MORE IN 2022

Most SARM companies sell liquid solutions because it is hard to justify that capsules or tablets are NOT for human consumption, so the legal risk of selling caps/tabs is greater.

Solutions allow the user to adjust the dose as desired, whereas capsules only allow the users to take 10, 20, 30mg… But never 5, 15 or 25 unless the capsules are opened, which is a pain in the ass. The main pro of capsules is ease of use and the lack of a disgusting taste.

Regardless of what format you choose, you should always take the SARMs in the morning, but it does not matter whether you have an empty stomach or not.

If the SARM you are taking has a short or unclear half-life, you should split the dose and take 1/3 in the morning, 1/3 after lunch and 1/3 before bed. If that is not possible, just do morning and evening.

If the compound you are taking has a half-life between 10 and 18 hours, take half the dose in the morning and the other half before bed.
Lastly, if the compound you are taking has a half-life longer than 18 hours, just take the entire daily dose in the morning.

Some people claim that taking SARMs with a short half-life before a workout gives them a boost in performance, so if you want to try that out, take 1/2 or 1/3 of the daily dose 1 hour before working out.
Ibutamoren (which is not a SARM) can be taken either in the morning or at night. By taking it at night you may be able to
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avoid feeling hungry the next day, but if you are bulking up and need a hunger boost, take it first thing in the morning.

Capsules and tablets are self-explanatory, just swallow them with some water. Administering liquids is also simple.
Unless you are consuming SR-9009 or SR-9011, simply put the liquid in your mouth with a dropper or a dispenser, swallow and then chase it with water or a tasty drink (preferably without sugar since that could interfere with your macros) to get rid of the nasty taste and prevent throat irritation.

ALWAYS SHAKE THE BOTTLE BEFORE USE.

If you are using one of the two SRs, put the liquid (or the powder) under your tongue and hold it there for up to 2-3 minutes. You can then spit out the remaining liquid/powder and drink some water to flush your mouth.

Liquid SARM bottles always have an mg/ml value in their label. This value indicates how many milligrams (mg) of the SARM are suspended in each milliliter (ml). The label will also specify how many ml the bottle contains in total.

Understanding these values is crucial for being able to dose the SARM properly, for example: 191

If a bottle has a total capacity of 30ml and the mg/ml concentration is of 20mg/ml, this means that each ml contains 20mg of the SARM, and the bottle contains a total of 600mg of the SARM (20mg x 30ml).

If you want to take 10mg/day of this particular SARM, you must take 0.5ml of liquid a day, which usually equates to half a dropper.

If you want to take 20mg/day, you will have to take 1ml of liquid a day, so a full dropper.

With all due respect, you should not be using SARMs if you have a hard time understanding this concept.

Some people say that it takes up to 4 weeks for the effects of SARMs to kick in, whereas others claim they can feel the positive effects the first day of a cycle.

Theoretically, most SARMs are at 99% efficacy after 6 days.

Most people feel a boost in strength and performance during the first week, and noticeable gains in muscle mass around week 3. Immediate gains in strength are usually just a placebo effect, but there is nothing wrong with it so embrace it.

In general, steroids blow SARMs out of the water. You can reach a level of muscular development with Steroids that is simply unobtainable with SARMs.

However, some SARMs are stronger than some Steroids. For example: LGD-3303 is probably as strong if not stronger than orals like Anavar, Turinabol and Epistane.

RAD-140 is stronger than Proviron and will definitely build more muscle in 8 weeks than Primobolan and maybe even Equipoise.
We could argue that the strongest SARMs are stronger than the weakest Steroids when each compound is used at its recommended dosage.

It is also worth noting that most SARMs are stronger than most Steroids milligram per milligram. For example, taking 5 mg/day of Ligandrol will yield more gains than taking 5mg/day of almost any Steroid.

In general, steroids are more dangerous than SARMs.

S-23, YK-11 and LGD-3303 are the only SARMs that have side-effects comparable to those of AAS. The rest of SARMs, however, are way safer than the majority of AAS, maybe with the exception of Proviron. They do not cause shutdown, they do not affect cholesterol as much as most steroids do, they are less liver toxic and they are less likely to cause side-effects like acne, gynecomastia and hair loss.

Some people argue that steroids are safer than SARMs because they have been around for so long that we know exactly what side-effects they have in the short and long term, whereas SARMs are so new that we only know the short term side-effects, but ignore the long-term ones. This is a good point, but the same people who say this tend to use Steroids like Equipoise and Trenbolone which were developed for horses and cattle and have no human clinical trials whatsoever.

I would not recommend stacking any SARM with any oral steroid with the exception of YK-11.

If you are on a heavy steroid cycle, adding a SARM won’t do much. For example, if you are taking 250mg of Test per week, 350mg of Tren Ace a week, 50mg of Winstrol a day and 100mg of Proviron a day, adding something like Testolone or even a stronger SARM like S-23 would be pointless.

In my opinion, Testosterone is the only Steroid that SARMs are really worth stacking with, but I would not recommend taking more than 250mg/week of Testosterone with a SARM since the SARM has a higher binding affinity for SHBG and for the androgen receptor, meaning that your free Testosterone will skyrocket which can lead to serious estrogenic and androgenic side-effects in some people.

Injectable SARMs gained a lot of popularity in late 2019. For a couple of months, it was the most discussed topic in the enhanced bodybuilding community, and everyone wanted to learn more about them because they were being marketed as being way stronger than the orals while having less side-effects. In early 2020, injectable SARMs went out of fashion when it became clear that such claims were not 100% accurate. Even though countless anecdotal reports show that injectable SARMs are more powerful than the orals on a mg-to-mg basis, the side-effects are equally if not more devastating.

Only liver toxicity is milder with the injectables than with the orals since the former skip the first pass of the liver. Testosterone suppression and dyslipidemia will still happen, and side-effects like hair loss and acne are way more prevalent and severe with injectable SARMs than with the orals. The modest improvement in gains does not justify the increased side-effects and the inconvenience of injections in the eyes of most researchers. Only YK-11 appears to be significantly better when injected, with many reporting more gains with similar side-effects.

In terms of non-SARM research chemicals, both injectable MK-677 and Cardarine are similar to their oral formulations, and only injectable SR-9009 and SR-9011 shine in comparison to their oral counterparts. The juice is not worth the squeeze with most injectable SARMs. After all, most SARMs already have great oral bioavailability. Only consider using Injectable SARMs if you are very experienced with a wide variety of oral and injectable anabolics.

There is a bill waiting to be passed in the USA which would put SARMs in the same category as Steroids and thus make them illegal. If the USA passes this bill, most European countries will do the same. This is the second bill that has been on the table for a while and ignored, however. It was ignored prior and scrapped the first time. Some SARMs and research chemicals are already banned in Australia and Russia.
Furthermore, China recently banned the production of most SARMs, so the supply chain has been interrupted. If no other country begins producing them, there will soon be a huge drop in supply. If the demand for SARMs does not decrease, the prices of SARMs will probably skyrocket.

As of May 2022, a handful of relatively popular SARM brands have received warning e-mails and letters from the FDA asking that they stop the sale of SARMs or face legal consequences. These companies were either selling capsules or marketing their products in a way that suggested that these products are for human consumption.

On paper, no one should take SARMs, but those under 21 should definitely not take them, for multiple reasons:
Firstly, their testosterone levels are high enough to provide incredible muscle gains naturally. If someone under 21 has bad testosterone levels, he can easily fix those with proper dieting, sleep and training, something that every bodybuilder, natural or enhanced, should do.
Secondly, they are so young that chances are they have not reached their genetic potential yet, so natural gains are still possible. It is also common for guys under 21 to be relatively new to the gym, and I believe that one should fall in love with the process before jumping on PEDs.

Finally, most teens are not mature enough to realize how important health is. This attitude often means that those under 21 see SARMs as just another supplement, and they do not prepare accordingly when planning a cycle.

SARMs were originally developed with the idea of helping people with muscle wasting diseases and osteoporosis, so old people are one of the target demographics that SARMs were developed for (from a therapeutic standpoint).
If we are talking about men in their 40s, 50s or even 60s using SARMs for performance enhancing purposes, then a few things must be taken into consideration.

The older we get, the more our health deteriorates. Most men in their twenties and thirties do not have to worry about their cholesterol, but men over 40 often have to be more careful with their cardiovascular health. For this reason, I believe that men over 40 must ALWAYS get bloodwork done before and after a cycle, to assess what their baseline is, to see what the impact of the SARM is and to see whether they have recovered or not. Cardio is especially important for older SARM users.

Testosterone is also something that declines with age, so men over 40 should monitor their levels and they should stay away from the more suppressive SARMs. Doing PCT would be wise, regardless of the cycle. In my opinion, men over 40 should only try the stronger SARMs if they are on TRT.

You have to keep a very important concept in mind when designing your cycle: SYNERGY. If you stack SARMs that provide similar effects like, for example, RAD-140 and LGD-4033, or Ostarine and ACP-105, you will not get 2x more gains, but you may get 2x more suppression and side-effects.

Use synergistic compounds that work through different pathways to achieve better results with less side-effects. I personally like to combine any SARM with YK-11 and/or MK-677.

MK-677 and/or Cardarine and/or SR-9009. All these compounds have a unique mechanism of action that doesn’t interfere with the others.

Due to changes in temperature, solutions may precipitate and/or crystallize. If that happens, you may see some chunks floating around and getting stuck to the dropper when you pull it out.

Simply heat up some water to the point where steam is coming out, but do not let it boil. Then leave the bottle inside for 1-2 minutes and after that, shake it well before examining the solution again. The particles should be almost fully gone. If, for whatever reason, you are unable to completely get rid of these particles, simply shake the SARM well before every use and take it anyway.

It is 100% possible to travel with SARMs, as long as they are legal (as research chemicals) in your country and your destination country. Still, it is normal for people to worry when preparing for a flight in which they intend to carry SARMs or other research chemicals, so here's a quick guide on how to do it for your ease of mind.

STEP 1: Do a quick Google search to make sure they are 100% legal (at least as research chemicals) in your destination country.
STEP 2: Put your RCs in your checked luggage and you are set. If you prefer to or you have to leave them in your carry-on bag, just put them in a smaller bag with other supplements or cosmetic products. There is nothing suspicious about the shape of the bottles, so you will not raise an eyebrow.

If they check manually and ask you what these products are, tell them that they are gym supplements. In the worst case scenario they will not know what these are, so they will test them to make sure they contain no illegal substances. I have yet to hear from someone who has experienced this, but if you do you will be fine (RCs are legal).

If you want to mitigate all risk, you can always put your SARMs in vitamin or skin serum containers.

Unfortunately, you will not find an accurate answer to this question. Different brands use different solvents, and each company claims their products have a different shelf life. For the most part, sealed liquid research chemical bottles are believed to have a shelf-life of 1 to 2 years and around 3 months if unsealed.

After this period, these products can still be used but they will have lost a ton of potency and they will continue to lose it as time goes on. There is no clear data on what the shelf life of SARM capsules/tabs is.

Keep in mind that these are just estimations based on what various companies have claimed and my own observations.
On a personal note, I have noticed a serious loss in potency from some products when using them a few months after they were unsealed and used for the first time. I have also tried sealed products from reputable brands that were 2+ years old and I barely got any effects from them.