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The best Post-Cycle Therapy (PCT) for SARMs has EVERYTHING to do with a class of drugs called SERMs. In SERMs 101, we taught you what a SERM is, how to use it for SARMs, what is the best PCT for SARMs, and lastly, where to buy SERMs for your SARMs post cycle.
If you need to brush up on the terms above, feel free to navigate to SERMs 101 and SARMs 101 before we dive deep into arguably the best SARM PCT on the market: Tamoxifen (Nolvadex).
If you’re just skimming, and looking for the #1 SARMs website to purchase PCTs from, we highly recommend Amino Asylum. Their high-quality products are second to none, and their shipping is ALWAYS on time.
WHAT IS TAMOXIFEN?
Tamoxifen (Nolvadex), like other SERMs we will explore, is a Selective Estrogen Receptor Modulators and is a class of drugs commonly used for the treatment of breast cancer, osteoporosis, and infertility in women. Tamoxifen is also employed by male bodybuilders, who use it to restore their endogenous hormone production after SARM/Steroid cycles (Post-Cycle Therapy) as well as to prevent and reverse gynecomastia.
TAMOXIFEN IN BODYBUILDING
SERMs can stimulate endogenous Testosterone production in males by blocking the hypothalamic estrogen receptor. This action tricks the brain into thinking that estrogen levels are low, and since estrogen is primarily acquired through the aromatization of Testosterone, the hypothalamus secretes GnRH which stimulates the pituitary causing it to release LH and FSH which boost Testosterone levels and sperm production.
IS A TAMOXIFEN PCT SAFE?
SERMs in general have been shown to be relatively safe and well tolerated and Tamoxifen is no exception to this. It has been clinically studied for treatment of osteoporosis in postmenopausal women at increased risk of fracture. Tamoxifen shows no breast or endometrial stimulation and in the first two years with patients taking drugs like Tamoxifen, the small increase is better in venous thromboembolism, and similar in the long term to other SERMs. [R]
In short, yes. Tamoxifen PCT studies have been heavily peer-reviewed and have proven their efficacy with little-to-no severe side-effects. More on the side-effects below.
Tamoxifen can increase Testosterone levels by stimulating the release of LH and FSH [R]. Off-label use of Tamoxifen by bodybuilders also confirms this phenomenon, with thousands upon thousands of men reporting good results and a complete reversal of their testosterone suppression after a PCT with Tamoxifen.
Tamoxifen is effective at preventing gynecomastia and reducing the size of already existing breast tissue [R]. It has been used by thousands if not millions of bodybuilders to prevent gynecomastia and to reduce its size if it has already developed.
As shown in this study, Tamoxifen can reduce total cholesterol and LDL cholesterol but its effects on HDL are unclear [R]. This benefit can help reverse the negative impact of the SARMs on your lipid panel; it can increase Triglycerides though.
While the risk of acquiring any side-effect(s) while using Tamoxifen during a PCT is low, we want our community to be fully knowledgeable about any potential dangers along the way in their research.
We also want to note here that many of the more severe effects were only shown to effect 1% of women taking Tamoxifen for years; all of which already had severe-to-fatal illnesses they were combating.
TAMOXIFEN PCT SIDE-EFFECTS
MOOD SWINGS AND SEXUAL DYSFUNCTION
While on your Tamoxifen PCT, it can cause terrible mood swings, anxiety, and depression in a very significant percentage of users.
Despite providing a modest increase in sexual function in some users, it is also possible for SERMs in general to have a negative impact on sex drive and erectile function. Mind you, many of the effects you’ll read here are empirical (not proven clinically).
HOT FLASHES AND NIGHT SWEATS
Tamoxifen can cause both hot flashes and night sweats in a small percentage of users [R].
Tamoxifen was proven to increase the chances of developing deep vein thrombosis (DVT) and pulmonary embolism (PE) in elderly women with breast cancer. Mind you, these studies have been done compiling data from Danish and Taiwanese databases. However, if you have a family history of DPV or PE, stay away from Tamoxifen and only use it for short periods of times if absolutely necessary. Fortunately, this is a rare side-effect, even in women with breast cancer who take Tamoxifen for years [R].
MILDLY LIVER TOXIC
Tamoxifen can potentially increase AST and ALT levels, but having a significant degree of liver toxicity due to most SERMs is extremely unlikely. Running N-Acetyl Cysteine (NAC) during PCT is always advisable [R].
HOW A TAMOXIFEN PCT WORKS
Tamoxifen works by selectively blocking estrogen receptors such as those found in the breasts and the hypothalamus. By antagonizing ERs in the breasts, Tamoxifen prevents estrogen from attaching to these receptors and causing the growth of breast cancer in females or gynecomastia in males.
Blocking ERs in the hypothalamus allows Tamoxifen to trick the brain into thinking that there is no estrogen in the body, causing it to stimulate testosterone production.
Even though all SERMs have the same mechanism of action, their effects differ slightly, making some more suitable for the treatment of gynecomastia, and others more effective at restoring / boosting testosterone production. Coming up, we’re going to show you where Tamoxifen really shines.
WHICH SARMS NEED A TAMOXIFEN PCT?
TAMOXIFEN PCT FOR SARMs
Not all SARMs require a Tamoxifen PCT. It’s best to run a post cycle therapy (PCT) after a SARMs cycle to get your natural testosterone levels back up to normal. While on cycle, your body will lower testosterone production because of the SARMs binding to androgen receptors, blocking out testosterone. Certain SARMs are more suppressive to testosterone production than others, although most of them are not as suppressive as an average steroid.
The only reliable way of determining whether a SARM needs a PCT or not is to get a blood test. If a blood test just isn’t in the cards for your research, it’s best to err on the side of caution and match the appropriate SERM with your SARM/AAS cycle.
The most common and our most recommended PCT consist of Tamoxifen. In circumstances where the cycle can be very suppressive, we recommend a double-PCT approach of Clomiphene (Citrate) and Tamoxifen PCT (we’ll discuss this shortly).
Some factors that affect these decisions could include type of SARM/AAS, dosage, cycle length, and genetic predispositions. We go into greater detail in our PCT for SARMs article.
SARMS THAT REQUIRE TAMOXIFEN
MILDLY SUPPRESSIVE CYCLES
For a mildly suppressive SARM cycle (Ostarine, ACP-105, Andarine, AC-262,536), Tamoxifen isn’t necessary but we always recommend it, especially in the absence of blood work.
ENHANCED LIFTING recommendation of 3 weeks of Tamoxifen at 10mg/day for the first two weeks followed by 5mg/day for the last week.
MODERATELY SUPPRESSIVE CYCLES
Moderately suppressive SARM cycles (LGD-4033 or RAD-140) only need one SERM still but you will have to take it at a higher dosage and for a longer period of time.
ENHANCED LIFTING recommendation of 20mg/day for the first 3 weeks and 10mg/day for the final week of your Tamoxifen PCT.
HIGHLY SUPPRESSIVE CYCLES
Highly suppressive SARM cycles (YK-11, S-23, & LGD-3303) tend to require two SERMs. These kinds of cycles have typically been followed by a Tamoxifen + Clomiphene PCT.
ENHANCED LIFTING recommendation of 20mg/day for three weeks of Tamoxifen and 50mg/day for three weeks of Clomiphene (Clomid); this is followed by 10mg/day of Tamoxifen and 25mg/day of Clomiphene for the final 4th week on your PCT.
WHERE TO BUY TAMOXIFEN
Now that we’ve reviewed the best SARM PCT on the market in 2023, let’s explore the best SARM websites, and we’ll tell you who we think the best companies are in 2023.
All of the vendors on this list have been carefully picked by our team, and every one of them assures high-purity active ingredients, moneyback guarantees, and touts high customer reviews.
While we can’t say one or the other has better Tamoxifen, we will split them up between there oral administrations of pill and liquid.
Getting a Tamoxifen
Not all of these SARMs websites sell PCTs like Tamoxifen (Nolvadex), especially in liquid form.
One of the reasons we really like Amino Asylum so much is because they have such a wide range of PCT products for sale. They carry Tamoxifen, Clomiphene, Raloxifene, & Enclomiphene all in liquid form!
Key benefits of Amino Asylum:
- Competitive Prices
- One-Stop Shop
- Good Customer Support
- Fast Shipping
- High-Quality Products
Amino Asylum is definitely one of the newer SARMs and research chemical companies on the block but they’re very quickly starting to build up a good reputation for their company, due to many customers giving raving reviews for their products.
In addition to this, if you use the code ENHANCED20 when purchasing, you’ll save 20% off your Tamoxifen (Nolvadex), your Clomiphene (Clomid), and anything else you want to buy.
Our favorite vendor for getting a good PCT for your SARMs is Amino Asylum.
Here are the prices with a 20% discount of Amino Asylum PCTs for sale:
- Tamoxifen (Nolvadex) 20mg/mL = $23.99
- Clomiphene (Clomid) 20mg/mL = $19.99
- Enclomiphene 20mg/mL = $31.99
- Raloxifene 30mg/mL = $27.99
Swiss Chems is one of the best SARMs companies out there due to their product purity, great customer support, and competitive prices. They’ve got some of the best research chemicals and PCT capsules on the market right now.
Here’s why we love Swiss Chems:
- Pharmacy Grade Products
- Third Party Tested For Purity
- Worldwide Shipping
- Competitive Prices
We asked for a coupon code to give you guys—use the code ENHANCED10 for 10% off. This will apply to any of the SARMs, PCTs, or peptides that they’re selling on their site.
All of their PCTs for sale are third-party verified, meaning that every batch is tested by an independent laboratory to ensure at least 98%-99% purity.
Here are the prices with a 10% discount of Swiss Chems PCTs for sale:
- Clomiphene (Clomid) 25mg/cap = $62.95
- Tamoxifen (Nolva) 20mg/cap = $72
- Raloxifene 20mg/cap = $77.35
You can buy SARMs and peptides from them as well and for even cheaper if you choose the bulk options that they have for sale.
In summary, it’s definitely best if you run a post cycle therapy for a SARMs cycle, to bring natural testosterone production back to normal.
Most people will keep around 75% of their gains if they do a good SARMs PCT like Tamoxifen as we discussed up above here.
If you want to get 20% off your Tamoxifen PCT and anything else, then just use the code “Enhanced20” at checkout and you’ll save money with this Amino Asylum coupon code.
POST CYCLE THERAPY FOR SARMs eBook
This Post Cycle Therapy for SARMs article provides a very general overview of SERMs.
For more information, check out THE SARM HANDBOOK we’ve written to give you everything you need to know in order to use SERMs & other Research Chemicals in the most effective and safest way possible.
Think of it like your personal cheat sheet for any cycle you have planned to know exactly each chemical you need from the start, during, and after your cycle.
With nearly 300 reviews and over 7000 copies sold, this should be a no brainer when it costs the same as a McDonald’s run.
Grab The SARM Handbook: the best guide to post cycle therapy for SARMs here