WHAT IS YK11 (MYOSTINE)?
YK11 (YK-11 or Myostine) is the most intriguing and fascinating SARM one can possible use. It is a steroidal SARM of the 19-Nor (Nandrolone) family that is also supposed to act as a Myostatin inhibitor. On paper, these properties make it an extremely powerful and versatile compound that can be used to destroy plateaus as well as erase one’s genetic limits.
BUY YK11 (MYOSTINE)
BUY YK11 (MYOSTINE)
YK11 (MYOSTINE) HISTORY
Most of our SARM profiles have a company backing them. YK11 has no pharmaceutical company responsible for its development but a patent shows it was originally filed on March 28, 2018 (US 20180319890 A1).
They originally developed it for the treatment of muscle wasting caused by catabolic reactions in skeletal muscle is commonly observed in patients with sepsis
In a 2021 in vivo study with septic mice, YK-11-induced protein levels “was found to increase in the muscle of septic mice simultaneously with an increase in the levels of follistatin.” [R]
HOW TO BUY YK11 (MYOSTINE) LEGALLY
YK11 is a legal performance enhancing drug. Given that is has not been approved by the FDA, YK11 can be classified as a research chemical. Research chemicals are completely legal to buy and sell online and over-the-counter, as long as they are being marketed as research products for laboratory use only and not for human consumption.
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HOW DOES YK11 (MYOSTINE) WORK?
YK-11 works by attaching to the androgen receptor (partially) in muscle tissue and bones. There, it stimulates protein synthesis to accelerate muscle growth and bone density.
This mechanism of action is similar to that of Anabolic Steroids, but the difference is that Anabolic Steroids are not selective and they attach to androgen receptors in all kinds of tissues, whereas SARMs are as selective for muscle and bone mass as possible.
While YK-11 has been found to act like a SARM, it is notorious for inhibiting myostatin (where it derives its AKA name–Myostine) and increasing follistatin levels in the body. By decreasing myostatin levels and increasing follistatin levels, this directly correlates to an increase in protein synthesis and cell growth. [R] [R]
YK11 PROS & CONS IN A NUTSHELL
- MYOSTATIN INHIBITION/FOLLISTATIN INCREASE
- INCREASED MUSCLE MASS
- WILL IMPROVE STRENGTH NOTICEABLY
- WILL PROVIDE A FULL, PUMPED LOOK
- WILL INCREASE BONE DENSITY AND JOINT STRENGTH
- CAN ACCELERATE FAT LOSS
- WILL SUPPRESS TESTOSTERONE LEVELS (TO A SMALL EXTENT COMPARED TO OTHER ANABOLICS)
- WILL CAUSE DYSLIPIDEMIA
- VERY LIVER TOXIC
- MAY CAUSE ACNE
- MAY CAUSE AGGRESSION
- CAN STIFFEN JOINTS
BENEFITS OF YK11 (MYOSTINE)
The benefits of YK11 have been a major reason why this has been a top-tier choice for bodybuilders to add in their cycle protocol.
It’s very synergistic with other SARMs or AAS (Steroids) as it’s only a partial agonist to the AR, so, it won’t compete for the AR like other SARMs who might have a stronger affinity to bind than it does. Not only this, it provides one of the most wildly profound ways of building muscle through the inhibition of myostatin, a protein responsible for the inhibition of cell growth or protein synthesis.
Imagine unlocking even more potential for protein synthesis without having to substitute any of your other favorite chemicals…well, you can!
Myostatin is a protein that acts on the muscle cells to prevent muscle growth. From an evolutionary perspective, an extremely muscular body would be very inconvenient, so it makes sense for the body to have a mechanism that limits muscle growth.
The way YK-11 allegedly inhibits this protein is by inducing the production of Follistatin, an antagonist to Myostatin. The logic behind this mechanism is that the more you increase Follistatin, the less effective Myostatin will be at limiting muscle growth and the bigger you will be able to become. [R]
It is very anabolic so it will increase your muscle mass, but we do not know the extent to which it will do so, compared to other SARMs and steroids. YK-11 is often used as a “wingman” because it is theorized that by inhibiting myostatin, this SARM enhances the anabolic potential of whatever you stack it with.
Unfortunately, it is very common for YK-11 to cause stiff joints due to the myostatin inhibition, a side-effect that can compromise strength gains.
BETTER FAT LOSS AND VASCULARITY
INCREASE BONE DENSITY & JOINT STRENGTH
A lot of people report that their joints feel extremely weak and stiff when on YK-11. This makes complete sense because myostatin inhibition is directly correlated to decreased joint and ligament health.
This negative side-effect predisposes athletes to getting injured during YK-11 cycles. [R]
The extent to which YK-11 helps with recovery is unknown, but a LOT of people report a recovery level that is unmatched by any other SARM. That is another hint that YK-11 may in fact be an effective myostatin inhibitor.
Like S-23, it is often compared to Winstrol and Masteron, so cutting cycles with YK-11 are effective at bringing out the definition. Pumps are also improved, and a more 3D look is guaranteed with this SARM.
SIDE-EFFECTS OF YK11 (MYOSTINE)
While the side-effects of YK11 remain unclear because of a lack of studies, this is what we’ve gathered through empirical evidence from tens of thousands of users:
It will probably cause full-shut down when stacked with oral Anabolics so we would always recommend a Test. Base and a PCT. (More information on this in the chapters about On-Cycle Therapy and Post-Cycle Therapy).
The consequences of this drop in your testosterone levels can be:
- Decreased libido
- Weaker erections
- Lack of motivation
- Testicular atrophy
- Testicular pain
Thankfully, most users do not experience more than a couple of these and only for a very limited amount of time, usually by the end of the cycle and during the first week or two after the cycle is over.
It is worth noting that YK11, like all SARMs, will decrease your SHBG. This will lead to an increase in your free testosterone levels which usually causes libido, motivation and well-being to improve during the first few weeks of the cycle, until the suppression of the Total Testosterone levels offsets the increase in Free Testosterone. [R]
The impact of YK-11 on the lipid panel will be harder than that of most SARMs and it will be comparable to that of other oral Steroids.
This side-effect will not manifest itself by impacting the way you feel, so you will have no symptoms. Getting bloodwork at the end of a cycle will show the true impact of the SARM on your lipid panel.
SARMs impact everyone differently. You may get insane amounts of acne in your face but your friend’s skin may improve on YK-11.
HOW TO AVOID & REVERSE SIDE-EFFECTS
If you are planning to do a YK11 cycle and you want to make sure your results are as good as possible while minimizing all side-effects and preventing the nasty side-effects like gynecomastia, erectile dysfunction, and hair-loss, you need to read THE SARM HANDBOOK by @enhancedinfo.
YK11 (MYOSTINE) DOSAGE FOR BODYBUILDING
Bodybuilders use anywhere from 5mg to 20mg a day, but the sweetspot that most male users prefer is 10mg a day. Do your due diligence to remember the half-life of YK11 is unclear but most take it twice per day. For example, if you choose 10mg/day as your dose, you would take 5mg every 12 hours.
We don’t advise female users to take this SARM, however, if one does, we don’t recommend going over 5mg/day.
HOW TO CYCLE YK11
YK11 is rarely taken solo. While it yields promising results, we have very little empirical evidence to suggest it. It’s usually used in conjunction with another main chemical, like RAD-140 to supplement the effects of protein synthesis even further.
The most common YK11 (Myostine) cycle consists of 10mg a day, split between two daily doses, taken for a total of 8 weeks. The shortest YK-11 cycles are usually around 4 weeks and the longest ones can last for up to 12 weeks.
We really believe that 10mg a day for 8 weeks is the best approach to using YK11, since it’s a protocol that allows most people to get amazing results without experiencing seriously nasty side-effects.
These cycles are always followed by a 4 week Post-Cycle Therapy.
YK-11 ON-CYCLE THERAPY
It’s imperative you use a testosterone base with your YK11.
We can’t recommend Amino Asylum Enclomiphene enough. While using YK-11, a simple 12.5mg/day protocol of Enclomiphene can help keep your testosterone levels balanced, not causing any of the nasty symptoms from suppression or worse, a crash.
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YK11 POST-CYCLE THERAPY (PCT)
Since YK-11 can suppress testosterone levels to a potentially large extent, we recommend all users to do a Post-Cycle Therapy (PCT) after a YK11 cycle to restore natural testosterone levels and ensure the retention of muscle gains, strength and optimal sexual function.
The typical YK11 PCT consists of 4 weeks of Clomiphene (Clomid) or Enclomiphene (Androxal) use. You can learn more about the ideal PCT for SARMs here.
YK11 (MYOSTINE) TL:DR
In a nutshell, we could say that YK11 (Myostine) is an incredibly effective SARM that can potentially help build a significant amount of muscle mass and strength.
This is an excellent option for intermediate and expert users who want to add a very potent, synergistic chemical with their PED stack but also for experienced, enhanced lifters who simply want to use something not fully AAS (Steroids) that will still provide great results with less side-effects than say, Masteron.
Take YK11 2x per day every 12 hours.
WHERE TO BUY YK11 (MYOSTINE)
If you decide to do a YK11 cycle, choosing a reliable company to buy from is crucial, since buying it from a bad company could result in you getting no results or getting horrible side-effects due to being sold something that’s not actually YK11 but maybe an actual AAS (Steroid).
We recommend going with Chemyo YK11.
All of their SARMs vials come in 50 ml (milliliter) bottles, which is a full 20 ml more than the industry standard of 30 ml—that’s a 66% increase in the value you’re getting with these products.
Key benefits of Chemyo:
- Third Party Testing
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They have been in the game for half a decade and have truly become one of the most reputable and most respected providers for 99.9% pure SARMs and other research chemicals.
You can buy YK11 from them through the link below and use code ENH10 to save 10% off your order
10mg split 2x per day every 12 hours for 8 weeks.
Yes and no.
While it's technically a steroid of the 19-nor family, it acts as a SARM.
From thousands of empirical reports the benefits mentioned in our benefits section are from actual users who either used YK11 solo or in conjunction with other PEDs.